NATO Advanced Research Workshop on

HUMAN MONITORING FOR GENETIC EFFECTS,

The Alexander Hollaender Course “Humogef”

Kraków, POLAND 23.06.02.-27.06.02.

REPORT

from the training with the application of the Trad-SH assay

One of the training was design to apply a well known bioindicator based on screening of the gene mutations in Trad-SH assay. Although time for the training was rather short and not each team was able to accomplish a comparison between two separate treatments with the last one (combined treatment), the mutations induced by various doses of radiation screened and evaluated by sixteen international teams resulted in a very good dose response curves presented on figures 1 and 2.

Fig,1 and 2 Dose response curves for gene mutation frequency induced by radiation resulting from average of the measures performed with Trad-SH bioinicator. Figure 2b shows dispersion between measures reported by various teams of the NATO ARW “Humogef” participants.